The phosphodiesterase-5 enzyme, found in the smooth muscle cells of the arteries, is inhibited by Vidalista 10. These medications work by blocking this enzyme, which stops PDE-5 from breaking down cGMP. It causes the vascular smooth muscle to relax. It, which causes the blood vessels to dilate by phosphorylating several downstream effector molecules. An erection lasts longer when the penile arteries dilate. Furthermore, PDE5 enhances endothelial function and lowers vascular smooth muscle cell death in the corpus cavernosum.
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